AI4Meder
返回论文列表
论文ICLR 2026 Poster2026 年trustworthy medical AI

利用特征低维流形实现少样本全切片图像分类

ICLR 2026 Poster accepted paper at ICLR 2026. Few-shot Whole Slide Image (WSI) classification is severely hampered by overfitting. We argue that this is not merely a data-scarcity issue but a fundamentally geometric problem. Grounded in the manifold hypothesis, our analysis shows that features from pathology foundation models exhibit a low-dimensional manifold geometry that is easily perturbed by downstream models. This insight reveals a key potential issue in downstream multiple instance learning models: linear layers are geometry-agnostic and, as we show empirically, can distort the manifold geometry of the features. To address this, we propose the Manifold Residual (MR) block, a plug-and-play module that is explicitly geometry-aware. Code/project link: https://github.com/BearCleverProud/MR-Block

论文默认配图 - 医学影像计算

论文详情

英文标题
Exploiting Low-Dimensional Manifold of Features for Few-Shot Whole Slide Image Classification
作者
Conghao Xiong, Zhengrui Guo, Zhe Xu, Yifei Zhang, Raymond Kai-yu Tong, Si Yong Yeo, Hao Chen, Joseph JY Sung, Irwin King
期刊/会议
ICLR 2026 Poster
发表年份
2026 年
研究方向
trustworthy medical AI