搜索医学 AI 论文与资源

ICLR 2026 Poster accepted paper at ICLR 2026. The rapid progress of visual autoregressive (VAR) models has brought new opportunities for text-to-image generation, but also heightened safety concerns. Existing concept erasure techniques, primarily designed for diffusion models, fail to generalize to VARs due to their next-scale token prediction paradigm. In this paper, we first propose a novel VAR Erasure framework **VARE** that enables stable concept erasure in VAR models by leveraging auxiliary visual tokens to reduce fine-tuning intensity. Building upon this, we introduce **S-VARE**, a novel and effective concept erasure method designed for VAR, which incorporates a filtered cross entropy loss to precisely identify and minimally adjust unsafe visual tokens, along with a preservation loss to maintain semantic fidelity, addressing the issues such as language drift and reduced diversity introduce by na\"ive fine-tuning.

ICLR 2026 Poster accepted paper at ICLR 2026. Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Electrocardiograms (ECGs) are the most widely used non-invasive tool for cardiac assessment, yet large, well-annotated ECG corpora are scarce due to cost, privacy, and workflow constraints. Generating ECGs can aid mechanistic understanding of cardiac electrical activity, enable the construction of large, heterogeneous, and unbiased datasets, and facilitate privacy-preserving data sharing. Generating realistic ECG signals from clinical context is important yet underexplored. Recent work has leveraged diffusion models for text-to-ECG generation, but two challenges remain: (i) existing methods often overlook physiological simulator knowledge of cardiac activity; and (ii) they ignore broader, experience-based clinical knowledge grounded in real-world practice.

ICLR 2026 Poster accepted paper at ICLR 2026. Diffusion models have recently emerged as powerful priors for solving inverse problems. While Computed Tomography (CT) is theoretically a linear inverse problem, it poses many practical challenges. These include correlated noise, artifact structures, reliance on system geometry, and misaligned value ranges, which make the direct application of diffusion models more difficult than in domains like natural image generation. To systematically evaluate how diffusion models perform in this context and compare them with established reconstruction methods, we introduce DM4CT, a comprehensive benchmark for CT reconstruction. Code/project link: https://github.com/DM4CT/DM4CT

ICLR 2026 Poster accepted paper at ICLR 2026. Generative models of 3D cardiovascular anatomy can synthesize informative structures for clinical research and medical device evaluation, but face a trade-off between geometric controllability and realism. We propose CardioComposer: a programmable, inference time framework for generating multi-class anatomical label maps from interpretable ellipsoidal primitives. These primitives represent geometric attributes such as the size, shape, and position of discrete substructures. We specifically develop differentiable measurement functions based on voxel-wise geometric moments, enabling loss-based gradient guidance during diffusion model sampling. Code/project link: https://github.com/kkadry/CardioComposer

ICLR 2026 Poster accepted paper at ICLR 2026. 3D medical imaging is in high demand and essential for clinical diagnosis and scientific research. Currently, diffusion models have become an effective tool for medical imaging reconstruction thanks to their ability to learn rich, high‑quality data priors. However, learning the 3D data distribution with diffusion models in medical imaging is challenging, not only due to the difficulties in data collection but also because of the significant computational burden during model training. A common compromise is to train the diffusion model on 2D data priors and reconstruct stacked 2D slices to address 3D medical inverse problems. Code/project link: https://github.com/duchenhe/ISCS

ICLR 2026 Poster accepted paper at ICLR 2026. Diffusion models have recently demonstrated significant robustness in medical image segmentation, effectively accommodating variations across different imaging styles. However, their applications remain limited due to: (i) current successes being primarily confined to 2D segmentation tasks—we observe that diffusion models tend to collapse at the early stage when applied to 3D medical tasks; and (ii) the inherently isolated iteration along timesteps during training and inference. To tackle these limitations, we propose a novel framework named Cross-Timestep, which incorporates two key innovations: an Adaptive Priori Decoding Strategy (APDS) and a trans-temporal memory LSTM (tLSTM) mechanism. (i) The APDS provides prior guidance during the diffusion process by employing a Priori Decoder(PD) that focuses solely on the conditional branch, successfully stabilizing the reverse diffusion process.

ICLR 2026 Poster accepted paper at ICLR 2026. Generating high-resolution 3D CT volumes with fine details remains challenging due to substantial computational demands and optimization difficulties inherent to existing generative models. In this paper, we propose the Pixel-Level Residual Diffusion Transformer (PRDiT), a scalable generative framework that synthesizes high-quality 3D medical volumes directly at voxel-level. PRDiT introduces a two-stage training architecture comprising 1) a local denoiser in the form of an MLP-based blind estimator operating on overlapping 3D patches to separate low-frequency structures efficiently, and 2) a global residual diffusion transformer employing memory-efficient attention to model and refine high-frequency residuals across entire volumes. This coarse-to-fine modeling strategy simplifies optimization, enhances training stability, and effectively preserves subtle structures without the limitations of an autoencoder bottleneck.