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论文ICLR 2026 Poster2026 年医学影像

Mini Experts 混合:突破多实例学习中的线性层瓶颈

ICLR 2026 Poster accepted paper at ICLR 2026. Multiple Instance Learning (MIL) is the predominant framework for classifying gigapixel whole-slide images in computational pathology. MIL follows a sequence of 1) extracting patch features, 2) applying a linear layer to obtain task-specific patch features, and 3) aggregating the patches into a slide feature for classification. While substantial efforts have been devoted to optimizing patch feature extraction and aggregation, none have yet addressed the second point, the critical layer which transforms general-purpose features into task-specific features. We hypothesize that this layer constitutes an overlooked performance bottleneck and that stronger representations can be achieved with a low-rank transformation tailored to each patch's phenotype, yielding synergistic effects with any of the existing MIL approaches.

论文ICLR 2026 Poster2026 年clinical prediction

面向数据高效精准肿瘤学的病理组学多模态结构表征学习

ICLR 2026 Poster accepted paper at ICLR 2026. Fusing histopathology images and genomics data with deep learning has significantly advanced precision oncology. However, genomics data is often missing due to its high acquisition cost and complexity in real-world clinical scenarios. Existing solutions aim to reconstruct genomics data from histopathology images. Nevertheless, these methods typically relied only on individual case and overlooked the potential relationships among cases. Additionally, they failed to take advantage of the authentic genomics data of diagnostically related cases that are accessible from training for inference. In this work, we propose a novel Multi-modal Structural Representation Learning (MSRL) framework for data-efficient precision oncology. Code/project link: https://github.com/WkEEn/MSRL

论文ICLR 2026 Poster2026 年clinical prediction

通过概念型多模态协同适配桥接放射学与病理学基础模型

ICLR 2026 Poster accepted paper at ICLR 2026. Pretrained medical foundation models (FMs) have shown strong generalization across diverse imaging tasks, such as disease classification in radiology and tumor grading in histopathology. While recent advances in parameter-efficient finetuning have enabled effective adaptation of FMs to downstream tasks, these approaches are typically designed for a single modality. In contrast, many clinical workflows rely on joint diagnosis from heterogeneous domains, such as radiology and pathology, where fully leveraging the representation capacity of multiple FMs remains an open challenge. To address this gap, we propose Concept Tuning and Fusing (CTF), a parameter-efficient framework that uses clinically grounded concepts as a shared semantic interface to enable cross-modal co-adaptation before fusion. Code/project link: https://github.com/HKU-MedAI/CTF; https://github.com/neuronflow/BraTS-Toolkit

数据资源histopathology whole-slide imagesdigital pathology whole-slide image datasetCAMELYON17 challenge dataset; see Grand Challenge page申请访问

CAMELYON17 组织病理淋巴结转移数据集

CAMELYON17 is a digital pathology dataset for detecting breast cancer metastases in lymph node whole-slide images across multiple centers. It supports pathology classification, metastasis detection, weakly supervised learning, and domain generalization in histopathology AI.

技术竞赛Openbreast cancer histopathology semantic segmentationH&E whole-slide histopathology images开始 北京时间 2026-05-03

BEETLE 乳腺癌组织病理分割挑战

Grand Challenge official API lists this medical AI challenge with status OPEN. BEETLE is a multicenter, multiscanner benchmark for breast cancer histopathology segmentation. It focuses on multiclass semantic segmentation of hematoxylin and eosin (H&E)-stained whole-slide images (WSIs) into four tissue categories: invasive epithelium, non-invasive epithelium, necrosis, and other. The evaluation set comprises 170 densely annotated regions from 54 WSIs, covering all molecular subtypes and histological grades, thereby capturing much of the morphological heterogeneity seen in clinical practice. BEETLE provides a standardized resource for benchmarking breast cancer segmentation models, supporting the development of robust, generalizable algorithms for large-scale biomarke...