论文ICLR 2026 Poster2026 年trustworthy medical AI 面向多模态癌症生存分析的结构化预后事件建模
ICLR 2026 Poster accepted paper at ICLR 2026. The integration of histology images and gene profiles has shown great promise for improving survival prediction in cancer. However, current approaches often struggle to model intra- and inter-modal interactions efficiently and effectively due to the high dimensionality and complexity of the inputs. A major challenge is capturing critical prognostic events that, though few, underlie the complexity of the observed inputs and largely determine patient outcomes. These events---manifested as high-level structural signals such as spatial histologic patterns or pathway co-activations---are typically sparse, patient-specific, and unannotated, making them inherently difficult to uncover.
论文ICLR 2026 Poster2026 年clinical prediction 面向数据高效精准肿瘤学的病理组学多模态结构表征学习
ICLR 2026 Poster accepted paper at ICLR 2026. Fusing histopathology images and genomics data with deep learning has significantly advanced precision oncology. However, genomics data is often missing due to its high acquisition cost and complexity in real-world clinical scenarios. Existing solutions aim to reconstruct genomics data from histopathology images. Nevertheless, these methods typically relied only on individual case and overlooked the potential relationships among cases. Additionally, they failed to take advantage of the authentic genomics data of diagnostically related cases that are accessible from training for inference. In this work, we propose a novel Multi-modal Structural Representation Learning (MSRL) framework for data-efficient precision oncology. Code/project link: https://github.com/WkEEn/MSRL