搜索医学 AI 论文与资源

ICLR 2026 Poster accepted paper at ICLR 2026. DNA methylation (DNAm) is a key epigenetic modification that regulates gene expression and is pivotal in development and disease. However, profiling DNAm at genome scale is challenging: of $\textasciitilde$28 million CpG sites in the human genome, only about 1–3\% are typically assayed in common datasets due to technological limitations and cost. Recent deep learning approaches, including masking-based generative Transformer models, have shown promise in capturing DNAm–gene expression relationships, but they rely on partially observed DNAm values for unmeasured CpGs and cannot be applied to completely unmeasured samples. To overcome this barrier, we introduce MethylProphet, a gene-guided, context-aware Transformer model for whole-genome DNAm inference without any measured DNAm input.

ICLR 2026 Poster accepted paper at ICLR 2026. Estimating heterogeneous treatment effects (HTEs) from right-censored survival data is critical in high-stakes applications such as precision medicine and individualized policy-making. Yet, the survival analysis setting poses unique challenges for HTE estimation due to censoring, unobserved counterfactuals, and complex identification assumptions. Despite recent advances, from causal survival forests to survival meta-learners and outcome imputation approaches, evaluation practices remain fragmented and inconsistent. We introduce SurvHTE‐Bench, the first comprehensive benchmark for HTE estimation with censored outcomes. The benchmark spans (i) a modular suite of synthetic datasets with known ground truth, systematically varying causal assumptions and survival dynamics, (ii) semi-synthetic datasets that pair real-world covariates with simulated treatments and outcomes, and (iii) real-world datasets from a twin study (with known ground truth) and from an HIV clinical trial.

ICLR 2026 Poster accepted paper at ICLR 2026. In precision medicine, quantitative multi-omic features, topological context, and textual biological knowledge play vital roles in identifying disease-critical signaling pathways and targets, guiding the discovery of novel therapeutics and effective treatment strategies. Existing pipelines capture only one or two of these—numerical omics ignore topological context, text-centric LLMs lack quantitative grounded reasoning, and graph-only models underuse rich node semantics and the generalization power of LLMs—thereby limiting mechanistic interpretability. Although Process Reward Models (PRMs) aim to guide reasoning in LLMs, they remain limited by coarse step definitions, unreliable intermediate evaluation, and vulnerability to reward hacking with added computational cost. These gaps motivate jointly integrating quantitative multi-omic signals, topological structure with node annotations, and literature-scale text via LLMs, using subgraph reasoning as the principle bridge linking numeric evidence, topological knowledge and language context.

This Frontiers Research Topic calls for work on integrating multi-omics data with clinical information to improve diagnosis, prognosis, and personalized treatment. The page lists a manuscript deadline of 2026-09-14 and is currently accepting articles, making it a relevant journal CFP for clinical translation, multimodal medical AI, and precision medicine.

CCF-Deadlines lists APBC 2026 with papers due 2026-06-15 UTC+0 and conference dates 2026-10-21 to 2026-10-24 in Hsinchu. APBC is directly relevant to medical AI through bioinformatics, computational biology, multi-omics modeling, precision medicine, and AI-assisted biomedical discovery.

IEEE BIBM 2026 covers bioinformatics, biomedicine, and health informatics, including machine learning and AI, biomedical image analysis, biomedical signal analysis, clinical decision support, EHR standards, healthcare knowledge representation, NLP and text mining, and precision medicine. The official CFP lists electronic submission of full papers due 2026-07-05, notification on 2026-09-25, camera-ready on 2026-10-25, and the conference on 2026-12-01 to 2026-12-04 in Dallas.

MIT OCW 6.S897 Machine Learning for Healthcare introduces clinical data and machine learning for risk stratification, disease progression modeling, precision medicine, diagnosis, subtype discovery, medical imaging, public health, and clinical workflow improvement.